KliniPharm Nature, innovated.
  Skin rejuvenation Deutsche Version
 Philosophy   |   Company   |   Products   |   Research   |   Contact Us
SpongiCol · vesigel · Beauty & Wellness


> What is Ulcerative
> Why existing
   treatments aren’t
> How SpongiCol can make
   a difference

Medications: Risk versus Benefit

For mild to moderate ulcerative colitis (UC) doctors prescribe drugs that target the inflammation in the colon. A class of drugs called mesalamines, also known as 5-aminosalicyclic acids (5-ASA), can be taken either orally or via suppository. Mesalamines provide intestinal relief by reducing inflammatory mediators and are thus used for maintenance of remission and to control flare-ups, but do carry risks and side effects. 5-ASA is the active moiety of the precursor drug, sulfasalazine, which has been traditionally used to treat UC symptoms. However, its side effects can be more intense compared to mesalamine derivatives. Additionally, patients who have a sulfa allergy cannot take sulfasalazine-based medications. Mesalamines were derived in the 1990s to give patients the benefits of 5-ASA and may be taken by those with a sulfa drug allergy, but carry a similar side effect pattern to sulfasalazine including headache, fever, diarrhea, abdominal pain, nausea, and skin rashes.

For moderate to severe symptoms during flare-ups, Corticosteroids can be used to reduce inflammation by suppressing the body’s immune system. Side effects are numerous and often include acne, insomnia, tremors, significant weight gain and type 2 diabetes. In severe cases, these drugs can cause increased blood pressure, osteoporosis, depression, cataracts and glaucoma.

For more severe symptoms that do not respond to 5-ASA drugs, immunomodulatory medications are usually prescribed. These drugs can be used with corticosteroids to bring a patient into remission and to maintain remission by targeting the irregular immune response that is exhibited in UC. Unfortunately, immunomodulators can take several months to exhibit an effect, have serious side effects, including increased risk for infection and cancer.

For many patients with UC, medication therapy is simply not enough and approximately 25-40% will require surgery to remove portions of their colon. After years of failed drug therapy and suffering from serious and frequent side effects, it can be devastating for patients to realize that surgery is their only option. Furthermore, post-operative complications such as severe diarrhea are common.

Thanks to SpongiCol®, surgery and years of needless suffering may no longer be inevitable for patients with UC by introducing this innovative nutraceutical to their treatment regimen.

Vitamin Supplementation: Solution or Distraction?

 Given the prevalence of UC, hundreds to thousands of complementary therapies have been advertised for the treatment of this condition. Unfortunately, some claims may carry less weight than others, providing patients with little to no relief from their symptoms while simultaneously emptying their pocket books and testing their patience.

While it is true that many patients with UC have vitamin deficiencies, simply supplementing one’s diet with these vitamins and nutrients is not a solution because the deficiency primarily stems from the inefficient absorption through the gut wall. Additionally, the drugs used to treat UC may further contribute to vitamin and nutrient deficiency by altering their endogenous metabolism. Indeed, vitamin and nutrient supplementation is an important part of maintaining health, but ingesting additional supplements while the colon wall remains diseased will not necessarily reverse the deficiency. Furthermore, some of the supplements may interfere with UC medications, rendering them less effective.

SpongiCol® offers an approach that allows the colon wall to absorb more of the vitamins and nutrients naturally consumed by targeting the root of the problem. It is scientifically engineered to be safe to use with any prescribed UC medication. SpongiCol® is not a vitamin supplement. Unlike many complimentary therapies that are commercially available today, the science behind SpongiCol® sets it apart, because it aims to restore the wall of the colon. Click here to see how SpongiCol® works.

Lifestyle Changes: I feel like I’ve tried everything …

 Chances are, if you are one of the millions of individuals suffering from the effects of UC, you have attempted a myriad of lifestyle changes, including dietary restrictions, home remedies, physical activity, even psychotherapy or counseling. After a great deal of trial and error, many patients with UC accurately identify food and lifestyle triggers that exacerbate their condition, but most patients still live with the looming threat of yet another flare. While one person may sense a benefit from an activity like yoga, another may experience no relief whatsoever.

Holistic remedies are attractive, especially given that patients with UC are required to take medications for many years in order to control their disease. Unfortunately, there is little evidence demonstrating the efficacy of these lifestyle changes. SpongiCol® offers an equally, perhaps more, holistic approach, as it is an all-natural nutraceutical, that for some has reduced dependence on the medications traditionally used to treat UC.

order SpongiCol

< back to SpongiCol main page

Copyright ©2002-2017 KliniPharm GmbH, Hauptstraße 10, 65760 Eschborn, Germany
Terms of Use | Privacy Policy | Created by Citrus Design